General anatomy of cardiovascular system

  1.  Cardiovascular system
  2. It is a transport system that carries blood and lymph to and from the tissues
    of the body

      Types of circulation – 

Systemic circulation is the part of the cardiovascular system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart.

Left ventricle of heart—-artery – capillary—venule – vein — right atrium of heart—right ventricle — pulmonary artery (carry deoxygenated blood )—lung — four pulmonary vein (carry oxygenated blood ) – left atrium—left ventricle

Pulmonary circulation: Pulmonary circulation is the portion of the cardiovascular system which carries deoxygenated blood away from the heart, to the lungs, and returns oxygenated (oxygen-rich) blood back to the heart.

Right ventricle — pulmonary artery (carry deoxygenated blood)—lung — four pulmonary vein (carry oxygenated blood ) – left atrium

Portal circulation: any part of the systemic circulation in which blood passage through two sets of capillary before draining to the heart;

types :

1. Arterial portal system , EX: renal portal system

Heart – artery –1st set capillary (at renal glomeruli) –arteriole —2nd set capillary(at capillary plexus, surrounding the proximal and distal convoluted of nephron )  –vein —heart,

2. Venous portal system : EX: hepatic portal system

Heart – artery –1st set capillary (GIT) –vein —2nd set capillary (liver) –vein —heart

Blood
vessels
:
definition: they are close system of tubular passages which convey the blood
from the heart to the different parts of body and from body to heart

Functions of blood vessel:

  1. They transport the blood for
    nutrition, respiration and excretion of the waste products of the body
  2. Termo regulation     Classification of blood vessels
    1. Arteries: three types of artery
      1. large (elastic) artery,
      2. medium (muscular) sized artery,
      3. small artery
    2. Arterioles
    3. Capillaries
    4. Venules and veins                                                      SN: heart—elastic artery(aorta) —medium sized artery— small sized artery—arteriole—terminal arteriole—meta-arteriole – pre-capillary sphincter – capillary—venule –vein —heart              Generalized structure of blood vessels:

      From within outwards the artery presents three coats

      1.     Tunica intima: is consists of –

      endothelium

      subendothelial connective tissue

      internal elastic lamina

      2.      Tunica media :it is the thickest layer in case artery

      This layer consist of —

       circumferentially arranged smooth muscle cells with

       elastic lamina  and collagen fiber

       Tunica adventitia:  it is the thickest layer in case vein,it is formed by connective tissue rich in collagen and elastic fiber 

 Artery : definition : they are thick walled tubes which convey the
blood from heart to the capillaries

Types of artery :1. Elastic/ large artery 2. muscular / medium sized
artey  3. small sized artery 

Features of elastic artery 

tunica intima 

*endothelium with its basal lamina

*subendothelial
connective tissue
is present (contain
smooth muscle, collagen and elastic fibres)

*an inconspicuous internal elastic membrane 

( internal elastic membrane present but difficult to
visualized in histological slide due to large amount of elastic fibres present
in elastic artery)

 large amount
of elastic lamellae and 
smooth muscle cells present in between the elastic lamella

Relatively thinner form by connective tissue rich in collagen & elastic fibres 

Examples: Aorta/Pulmonary arteries Brachiocephalic arteries / Common carotid artery 

Features of muscular artery 

endothelium with its basal lamina

*subendothelial connective tissue is present

 (contain smooth muscle, collagen and

elastic fibres) and

*Prominent internal elastic membrane 

circumferentially arranged smooth muscle cells,

 with little elastic, collagen and reticular fibers 

Relatively thicker

form by connective tissue rich in collagen & elastic fibres ,

external elastic membrane separated it from the tunica media

Brachial artery, femoral artery, external carotid artery 

Small
artery / Arterioles: 
they are the smallest divisions of the muscular
arteries possessing three coats. They successively form terminal arteriole and
meta-arterioles. Meta –arteriole terminate as capillary.

Topics

Small arteries

Arterioles

Tunica
media

Up
to eight layers

Only
one or two layers

Internal
elastic membrane

Present

May
or may not present

Tunica
adventitia

Thin,
ill defined

Thin,
ill defined

 Pre-capillary sphincter: the slight thickening of the smooth muscle at
the junction of meta- arteriole and
the origin of a capillary bed is called
the pre-capillary sphincter

Functions
of arterioles:

  1. Regulate the amount
    of blood entering into the capillaries (by pre-capillary sphincter)

They offer peripheral resistance and regulate systolic arterial pressure 

 Anastomoses between arteries

Actual : Arteries meet end to end. EX: Labial branches of two facial arteries

Potential : Anastomoses is occurred by terminal arterioles,  It need sufficient time for dilatation , Sudden occlusion of main artery, this anastomoses is failed to nourish the affected part. Ex: coronary arteries

End artery: End arteries are those which do not form any pre-capillary anastomoses.

They are two types:

 

Functional end artery :contain insufficient pre-capillary anastomosis 

Example:   coronary arteries

True end artery:no pre-capillary anastomosis

 Example: Central artery of retina

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